2C-T-7

2C-T-7
The skeletal formula of 2C-T-7.
Chemical Nomenclature
Common names	2-C-T7
Substitutive name	2,5-Dimethoxy-4-n-propylthiophenethylamine
Systematic name	2-[2,5-Dimethoxy-4-(propylthio)phenyl]ethanamine
Routes of Administration
Oral Dosage Presumes no tolerance Threshold 3 - 5 mg Light 10 - 20 mg Common 15 - 30 mg Strong 10 - 50 mg Heavy 25 - 60mg Duration Total 5 - 10 hrs Onset 60 - 90 mins Peak 3 - 7 hours Offset 1 - 2 hours Afterglow 2 - 4 hours Insufflated Dosage Presumes no tolerance Threshold 1 - 3 mg Light 2 - 10 mg Common 5 - 15 mg Strong 5 - 20 mg Heavy 7 - 25 + mg Duration Total 3 - 7 hours Onset 5 - 15 mins Peak 2 - 4 hours Offset 1 - 2 hours Afterglow 1 - 2 + hours

2C-T-7 (2,5-dimethoxy-4-propylthiophenethylamine) is a psychedelic phenethylamine of the 2C-x family. It was first synthesized by Alexander Shulgin in his book PiHKAL: A Chemical Love Story. This particular substance is part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which except mescaline he developed and synthesized himself. They are found within the first book of PIHKAL, and are as follows: Mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7.

2C-T-7 is a highly dose sensitive psychedelic known for its strong visuals and intense body load. Many reports also indicate that the effects of this chemical may be overly intense for those who are not already experienced with psychedelics.

Chemistry

General formula of phenethylamine molecule.

2C-T-7 is a substituted phenethylamine with methoxy groups attached to carbons R₂ and R₅as well as a sulfide chain attached to carbon R₄. 2C-T-7 is nearly identical in structure to 2C-T-2. The two molecules differ in the length of their sulfide chain. 2C-T-7 contains a propyl thioether group while 2C-T-2 contains a ethyl thioether group.

Pharmacology

Main article: Serotonergic psychedelic

2C-T-7's psychedelic effects have been shown to come from its efficacy at the 5-HT_2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

As the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor, this substance may likewise have MAOI effects.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical effects

The physical effects of 2C-T-7 can be broken down into six components all of which progressively intensify proportional to dosage. These are described below and generally include:

• Spontaneous tactile sensations - The body high of 2C-T-7 is intense but, in comparison to 2C-E or 2C-B, it can be considered mild though is still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the body high experienced on 2C-E, 2C-B, and LSD. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
• Stimulation - In terms of its effects on the physical energy levels of the tripper 2C-T-7 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other phenethylamines such as 2C-B, 2C-E and 2C-P.
• Bodily control enhancement - Although this component is capable of manifesting itself in a distinct and noticeable fashion for most users it does not generally seem to be as apparent or intense as the same component found within LSD and 2C-B.
• Tactile enhancement
• Nausea - Mild to extreme nausea is commonly reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
• Temperature regulation loss
• Increased heart rate
• Pupil dilation

Cognitive effects

The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.

The total sum of these cognitive components regardless of the setting generally includes:

• Current mind state enhancement
• Thought acceleration
• Novelty enhancement
• Time distortion
• Analysis enhancement
• Personal bias suppression
• Conceptual thinking
• Memory suppression
• Thought loops
• Feelings of interdependent opposites
• Delusions
• Unity and interconnectedness

Visual effects

Enhancements

2C-T-7 presents a full and complete array of possible visual enhancements which generally includes:

• Visual acuity enhancement
• Colour enhancement
• Pattern recognition enhancement

Distortions

2C-T-7 presents a full and complete array of possible visual distortions which generally includes:

• Drifting (Melting, Flowing, Breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and extremely realistic in style but with a subtle digital/cartoonish form.
• Tracers
• After images
• Symmetrical texture repetition
• Colour shifting
• Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or Ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges and equally rounded and angular in their corners. They give off a contradictory natural and synthetic feel with slightly more mystical and shamanic undertones to them in comparison to other phenethylamines. At higher dosages they are equally likely to result in states of Level 8A visual geometry or Level 8B. There seems to be visual geometry that is extremely similar to 2C-E and 2C-P and can be described as equal in intensity or complexity and equal in proportion to the accompanying cognitive and physical effects.

Hallucinatory states

2C-T-7 produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the phenethylamine family. These effects include:

• Transformations
• Internal hallucinations (Autonomous entities, Settings, sceneries, and landscapes, Alterations in perspective and Scenarios and plots) - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, geometry-based in style and almost exclusively of a religious, spiritual, mystical, science fiction or transcendental nature in their overall theme.

Auditory effects

The auditory effects of 2C-T-7 are more common in their occurrence than many more commonly used psychedelics and exhibit a full range of effects which commonly includes:

• Enhancements
• Distortions
• Hallucinations

Toxicity and harm potential

Lethal dosage

The toxicity and long term health effects of recreational 2C-T-7 use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2C-T-7 is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried 2C-T-7 within the psychedelic community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

There is no current data for the LD₅₀ of 2C-T-7, but it is thought to be high.

Tolerance and addiction potential

2C-T-7 does not seem to be physically addictive and many users experience a self-regulating quality. There seems to be a tolerance build up when used consecutively multiple days in a row which requires one to double their dosage each time to achieve the same effects.

Interactions

If 2C-T-7 does have MAOI effects, this could indicate that 2C-T-7 is more likely to induce serotonin syndrome, especially at high dosages, than other serotonergic hallucinogens. This may make it dangerous to combine with certain substances such as MDMA, AMT, Ayahuasca or any substance which releases neurotransmitters such serotonin or those with similar pharmocological effects.

Legal issues

• 2C-T-7 is scheduled in Germany.
• In Australia, 2C-T-2 and 2C-T-7 are covered by the country's analogue drug laws.
• 2C-T-7 is unscheduled in Canada.
• The Netherlands was the first country in the world to ban 2C-T-7, after being sold in smartshops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market, but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.
• Schedule I in Sweden. 2C-T-7 was first classified as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of April 1, 1999 under SFS 1999:58 that made it illegal to sell or possess.
• In 1999, Alexander Shulgin was sent a copy of a letter from the British Home Office to several of its administrative associates that in effect placed all compounds listed in PiHKAL into Class A.
• On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a Final Rule in the Federal Register permanently placing 2C-T-7 in Schedule I.

See also

• 2C-T-2
• 2C-E
• 2C-B
• 2C-T-7 (Wikipedia)
• 2C-T-7 (Erowid)